a melanotic macule macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Figure 2 from Oral melanotic
Description
Cancer is characterized by dysregulated or reversed pH, with a higher intracellular pH (pH i 7.4) and a lower extracellular pH (pH e = 6.7-7.1) [165]

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