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Oxidative stress causes damage of lung promoting airway hyperresponsiveness and inflammation in asthma exacerbations

Bone 80 , 101108 (2015)

Mean smoking pack years was 40.32 35.18

The findings indicated that methanolic soursop leaf extract significantly diminished the incidence and burden of lung tumors, reduced the expression of the serum cancer marker carcinoembryonic antigen (CEA), lowered lipid peroxidation, and enhanced levels of superoxide dismutase (SOD), glutathione (GSH), and catalase (CAT) in comparison to control groups treated solely with BPa

Planta Med 75(10):11341140 Park S-J, Song H-Y, Youn H-S (2009) Suppression of the TRIF-dependent signaling pathway of toll-like receptors by isoliquiritigenin in RAW264.7 macrophages

Deloche C, Bastien P, Chadoutaud S, Galan P, Bertrais S, Hercberg S, de Lacharrire O