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Author contributions FP: Data curation, Formal analysis, Investigation, Validation, Writing original draft, Writing review & editing

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Glucocorticoids, for example, regulate the expression of glucocorticoid-sensitive genes by binding to glucocorticoid (GR) or mineralocorticoid receptors (MR) and subsequent activation of transcription through glucocorticoid/mineralocorticoid response elements ( GREs / MREs ) in gene regulatory regions 21,22