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PDI inhibitors are already being investigated as novel antithrombotic therapeutics and these findings highlight the importance of GSH in platelet aggregation, as well as a potential therapeutic

It has been found that SiO 2 NPs can exacerbate PD pathology by promoting -synuclein aggregation, mitochondrial impairment, OS, and neuronal apoptosis

Neurochem Res 48:32963315

J., Ahl, P

We thank Gong-Min Lin at Metabolomics Core Facility of Agricultural Biotechnology Research Center in Academia Sinica for the assistance of metabolomics analysis and 13 C metabolite tracing

The freshly treated hTrx1 has free thiol on surface Cys73 ( 2.7 Effect of thiol-reactive reagents on diamide-induced formation of TrxR1-hTrx1 complex The non-reduced TrxR1 was, respectively, pre-incubated with 10 mM H 2 O 2 , diamide, GSSG, GSNO, DTNB, IAM or IAA for 30 min at room temperature