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Description
Animal studies show that long-term carnitine supplementation promotes mitochondrial biogenesis in skeletal muscle, heart, and brain tissue of aging subjects through upregulation of PPAR-coactivator-1 (PGC-1), a master regulator of mitochondrial biosynthesis and function

23 : 18831883 Pisano C, Camerini B, Castorina M, Olivi A, Ambrosini A, Calvani M

& Snyder, S

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No significant differences in plasma levels were seen in the different dosage groups despite a reduction of the total daily dose by up to two thirds (from 1.5g twice daily to 1g once daily)

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