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Furthermore, certain BAs like ursodeoxycholic acid (UDCA) and ursocholic acid (UCA), associated with Lachnoclostridium enrichment, correlate with improved outcomes in HCC patients receiving immunotherapy (119)

p = 0.013) was significantly greater in the PLA group compared to the CAR group

These cells exhibit heightened glycolytic flux, which supports the production and release of pro-inflammatory cytokines like IL-1 and TNF-

The diagram indicates that ABCB7 deficiency leads to impaired stabilization of ferrochelatase because ABCB7 fails to provide sufficient support for Fe-S cluster incorporation into ferrochelatase

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It can also prevent skin aging and pigmentation, and reduce the formation of melanin