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Interestingly, the pentamer changes into the monomeric form after interacting with activated membranes through a procedure involving an intermediate CRP form known as monomeric CRP m or pentameric CRP*, a form which represents the initial stages of subunit dissociation, in which the still-pentameric protein begins expressing antigenic and functional attributes, which are characteristic of monomeric CRP [68]

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Although also used as a food supplement, choline alphoscerate is available as a prescription drug, and therefore subject to tight regulation and rigorous testing to provide evidence of effectiveness and safety (Hathcock, 2001

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