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doi: 10.1177/1759720X18776224
Therefore, under such oxidative stress conditions, GSH reversibly binds to the thiol residues to prevent irreversible changes in proteins due to oxidative stress

Clin Chem 55:15301538

Methotrexate induces an antioxidant hormetic response in primary rat astrocytes

noted an antidepressant-like effect on both wildtype and Huntington-disease murine models, which was noted to be due to decreased mitochondrial oxidative stress [33]

Regnault C, Soursac M, Roch-arveiller M, Postaire E, Hazebroucq G