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Safety in Context: Study Limitations While the clinical trial safety data for AOD-9604 is extensive and reassuring, understanding the limitations of this evidence base is essential for balanced interpretation

The combination therapy resulted in significant improvement in pain, fatigue, sleep, and depression compared to duloxetine and pregabalin alone

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Users often compare them to the kind of headache you get when slightly dehydrated or when adjusting to a new routine

doi: 10.1530/eje.0.1330425 128 FrieboesMurckAntonijevicSteiger
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