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RESULTS Hepatocyte Growth Factor Augments the dendritic architecture and Supports Synaptogenesis Dihexa and Nlel -AnglV have previously been .shown to induce spinogenesis in mRFP-p-actin transfected hippocampal neurons (see Example 1)

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In vivo reduction of age-dependent neuromelanin accumulation mitigates features of Parkinsons disease

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Clinically approved pharmaceutics Clinically approved drugs are a promising source of senotherapeutic agents due to their established safety profile in patients with relatively well-understood toxicities (Figure 2)

14 Growth factors such as RPR (Recombinant Platelet-Derived Growth Factor), BMP-2 (Bone Morphogenetic Protein-2), FGF (Fibroblast Growth Factor), VEGF (Vascular Endothelial Growth Factor), TGF- (Transforming Growth Factor-beta), and BGF (Basic Growth Factor) play crucial roles in driving cellular processes by activating specific receptor-mediated signaling pathways that influence cellular proliferation, migration, differentiation, and survival
