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GHK Restores TGF-Beta Pathway in COPD Lungs A collaborative study conducted by scientists from Boston University, University of Groningen, University of British Columbia, and University of Pennsylvania established that the GHK peptide reverses the gene expression signature of COPD, which is manifested by emphysema, inflammation, lung tissue destruction, and significant reduction of lung capacity

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Only one study exists that has reported this important data at the time of writing this review, and this did not include the malate component

& Roux, D

HNMT catalyzes the methylation of the secondary amine group of the histamine imidazole aromatic heterocycle by a reaction requiring the S-adenosyl methionine cosubstrate as a methyl group donor [11,13,19]