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Metallothionein, by virtue of its metal ion binding and antioxidant capacity, is able to reduce the damage caused by metal ions and oxidative stress on nerve cells [7,8]

Rate-limiting enzyme in the AMA pathway and its mechanism implication ALDH was identified as the rate-limiting enzyme in the AMA pathway based on three experiments: (i) Enzyme activity assay: Despite being more highly expressed than the other two enzymes, ALDH exhibited the lowest enzyme activity (Supplementary Fig

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