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Description
doi: 10.1016/j.cell.2017.03.035 132

His work focuses on how microbial ecosystems interact with human physiology, including: Gut barrier function and intestinal permeability Mucus-associated microbiota (Akkermansia-related systems) Oralgut microbiome axis Short-chain fatty acids (SCFAs) and metabolic signaling Circadian rhythmmicrobiome interactions Clinical Research Contributions He has contributed to multiple clinical-stage microbiome programs, supporting bacterial strain discovery, optimization, and formulation design across different therapeutic areas, including: Active Ulcerative Colitis (Inflammatory Bowel Disease) Hyperoxaluria (Oxalate Metabolism Disorder) Microbiome-driven gut health and inflammatory conditions These studies were part of broader clinical development programs evaluating microbiome-based approaches

Retatrutide E_max at GIPR 103%, GLP-1R 110%, GCGR 104% of native peptide peak (full agonist at all three at cAMP signaling per the conclusions section: "LY3437943 is a full agonist at the GCGR, GIPR, and GLP-1R in the functional assays")

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C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization

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