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GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses

This provides a unique, quantifiable biomarker of target engagement, making NSI-189 phosphate the compound of choice for studies focused on structural neural plasticity and hippocampal-dependent cognitive recovery

Inactivation of Capicua drives cancer metastasis

Temperature excursions above 8C cause irreversible structural changes that neither appearance nor home testing can detect

Until recently 17 , only high-resolution structures of the separate E1 and E2 subunits were available, but these did not provide the structural information to interpret the structure of E1E2 16,18,19,20,21

TB-500 distributes broadly through connective tissue, muscles, and joints throughout the body, which makes it particularly useful for patients dealing with multiple injury sites, diffuse connective tissue inflammation, or slower-healing chronic conditions that a localized peptide cannot fully address