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Lack of Nrf2 in this model also restored basal protein oxidation levels (measured by an increase in 4-hydroxynonenal modification, a byproduct of lipid peroxidation)

10.1126/scitranslmed.3007154 Sci Transl Med

This variability is in line with previous reports demonstrating significant differences between individual worms in neural activity patterns and behavioral outputs (Luo et al , 2014

[41] Whereas DNA methylation is not necessary per se for transcriptional silencing, it is thought nonetheless to represent a "locked" state that definitely inactivates transcription

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The marker table was sent to the EZinfo multivariate statistics software (Umetrics, Umea, Sweden) for data exploration by PCA and then data classification according to both anaerobic and aerobic groups using an OPLS-DA model