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Many payloads for ADC development can be conjugated to an antibody via disulfide linkers

Retinoid signaling play a physiological role in synaptic plasticity and learning and memory behaviors [188]
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The brain regions in which these genes are expressed include the amygdala, subgenual anterior cingulate, and dorsolateral prefrontal cortex, and the associated molecular pathways include reduced neurotrophic support, neural signaling, and GABA function

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