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The pathological changes of articular cartilage degradation and synovial hyperplasia were evaluated after receiving continuous GYY4137 intervention for two months (Fig

Symptoms of a Herxheimer reaction include a sudden, intense exacerbation of baseline symptoms: severe brain fog, debilitating fatigue, migrating joint pain, flu-like body aches, headaches, and heightened anxiety

Cellular senescence is considered one of the markers of aging

Targeting NAD + related enzymes NAMPT NAMPT is a pivotal enzyme in NAD + biosynthesis

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On a deeper level, a rescue experiment showed that the combination of sh-ALDH3A1 and the -elemene group caused a more potent inhibition of cell proliferation and DNA replication (Fig