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According to the leaky gut theory, these alterations in gut microbiota may be related to inadequate perfusion to the viscera due to cardiac congestion or impaired ejection capacity in patients with HF, and ischemic edema in the intestine caused by ischemia, which might increase the permeability of the intestinal epithelium (Sandek et al., 2007), thus allowing intestinal macrobiotic and bacterial metabolites to gain access to the circulatory system through the compromised barrier

However, other human studies have found opposing results

These studies not only deepen our understanding of the role of CEBPA in hepatocellular carcinoma, but also further confirm its great potential as a potential therapeutic target

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In turn, the presence of reactive oxidative species induces the formation, in particular from polyunsaturated fatty acids, of peroxidated lipids
