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3.6 Iron homeostasis regulation Iron accumulation in aged skeletal muscle is another factor that leads to increased lipid peroxidation and impaired regenerative capacity

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Zhang X, Xie H, Iaea D, Khelashvili G, Weinstein H, Maxfield FR (2022) Phosphatidylinositol phosphates modulate interactions between the StarD4 sterol trafficking protein and lipid membranes

3 The imbalance in NAD+/NADH ratios can lead to impaired cellular stress responses and metabolic dysfunctions, which are characteristic of metabolic diseases

In addition to proper blood pressure and glycemic control, therapeutic options to deter or revert the development of fibrosis are quite limited

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