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the ex vivo study employed 10 mol/L of melatonin in the culture medium for 2448 h) [183]

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The European Federation of Neurological Societies guidelines on neuropathy recommend pregabalin, gabapentin, duloxetine, tricyclic antidepressants, and venlafaxine for first-line treatment, with opioids and tramadol reserved for second-line therapy [37]