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10.1007/s11130-021-00879-7 58 HuangD.OuB.Hampsch-WoodillM.FlanaganJ

Riboflavin is critical to the proper functioning of mitochondrial pathways, and mitochondrial dysfunction linked to riboflavin deficiency is linked to many neurological conditions, including AD, PD, MS, Alper's syndrome, and Kearns Sayre Syndrome, reviewed in Ref

Pretreatment with NSAIDS is neuroprotective in MPTP and 6-OHDA-treated animals and in vitro (Esposito et al., 2007)

However, these studies are still not large enough and more robust studies would be required to justify its cosmetic use and safety

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As such, ergogenic aids, which can alleviate these negative effects by promoting alertness and augmenting physical performance, are of interest to military [23]