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The expression of the epithelial-mesenchymal transition transcription factor Snail leads to Scrib displacement from the plasma membrane to the cytosol, which is associated with disrupting S -palmitoylation of Scrib in epithelial cancer cells (77)

This activation facilitates the synthesis and secretion of various inflammatory factors by epidermal and dermal cells, including interleukin-1 (IL-1), interleukin-6 (IL-6), cyclooxygenase-2, and tumor necrosis factor-alpha (TNF-), which collectively induce inflammatory responses (85, 86)

24-Hour Urinary Sodium and Potassium Excretion and Cardiovascular Risk

Bryan, H

[DOI] [PMC free article] [PubMed] [Google Scholar] Sheppard RC