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This creates an extraordinarily high binding affinity with pK = 16.44, approximately 10 million times higher than other tripeptides and comparable to albumins copper binding (pK = 16.2)

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One compound of research interest is the human peptide GHK (glycyl-L-histidyl-L-lysine), a copper-binding peptide known for its diverse biological actions that have been studied in the context of aging-related diseases and conditions

Growth hormone receptor upregulation amplifies the cellular repair response

Available online: [PubMed] [Google Scholar] 101.Nezhad N.C., Vahabzadeh Z., Allahveisie A., Rahmani K., Raoofi A., Rezaie M.J., Rezaei M., Partovyan M

Rappuoli R, Aderem A