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Pharmacokinetic modeling and clinical experience support this approach, though no head-to-head randomized trial has compared 1.5 mg twice weekly versus 2.5 mg once weekly
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Ready-to-use sterile vials reduce waste and ensure patient safety
o In attack treatment : 1 ampoule per day for 15 days to 1 month
The foundational preclinical study was published by Neelakantan et al
The higher expression of IFN at earlier timepoint and higher populations of CD4+ and CD8+ cells are major contributors to clearance of BacA from tissue
