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In the second step, GSH synthetase adds glycine to -glutamylcysteine (-EC) to produce GSH ( Figure 1 )

359 Therefore, enhanced mitophagy is regarded as a strategy to alleviate neurodegeneration 360,361 by upregulating PINK1 and Parkin in neurons, thus increasing the activity of microglia to phagocytose A plaques, and improving cognitive and memory function
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Here, we characterized this behavior in more detail for the first time using a subjective visual human observation of a bottom-view videotape and an automatic DeepLabCut analysis

thereby, making modulation of neuronal oxidative load as one of the major approaches in management of PD

Thatcher, R
