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Gaugler T, Klei L, Sanders SJ, Bodea CA, Goldberg AP, Lee AB, et al

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This difference was likely attributable to the insufficient inhibition of excessive GJ proteins in hepsin / mice in response to the lower 2APB dose of 1 mg/kg, lending further support to the hypothesis that hepsin may help reduce APAP toxicity by regulating the expression of hepatic GJ proteins

Three major types of autophagic pathways, macroautophagy, microautophagy, and chaperone-mediated autophagy (CMA), have been recognized in eukaryotic cells (Mizushima and Komatsu, 2011)

doi: 10.1016/S0008-6363(01)00533-8

The small molecule has also been shown to help lower blood cholesterol levels and stimulate muscle repair in animal studies, paving the way for a host of research applications