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Male albino rats were divided into four groups ( n = 12 in each)control, calorie restricted (CR for 5 days, 25 % of basal food intake), L-carnitine supplemented (CAR, given orally for 5 days at a dose of 100 mg/kg), CR with L-carnitine supplementation (CR + CAR)

Upon crossing the inner mitochondrial membrane, ALCAR undergoes a fascinating biochemical split

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[1] Gamma-butyrobetaine is then hydroxylated by gamma butyrobetaine hydroxylase (a zinc binding enzyme [10] ) into l-carnitine, requiring iron in the form of Fe 2+

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