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After age 30, natural GH secretion declines by approximately 1415% per decade

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doi: 10.3389/fnut.2025.1686777 Received 15 August 2025 Revised 15 November 2025 Accepted 28 November 2025 Published 12 January 2026 Volume 12 - 2025 Edited by Andrea Orellana-Manzano, Escuela Superior Politcnica del Litoral (ESPOL), Ecuador Reviewed by Paulina Cerda Opazo, Autonomous University of Chile, Chile Aliakbar Fazaeli, Ardabil University of Medical Sciences, Iran Updates Copyright 2026 Garutti, de Scordilli, Alberti, Mazzeo, Michelotti, Fagioli, Del Conte, Casirati, Caccialanza, Bartolini and Puglisi

Taking advantage of the power of the MS analysis, we observed that HBMEC metabolized the phenolic sulfates into novel metabolites, mainly glutathione and glucuronic acid derivatives

The bipartite network was created to highlight the common genera among samples, employing the div_network function from the gg ClusterNet package in R version 4.2.0.1 [18, 19]

In treating solid tumors, developing more tumor-targeting ASNase is one aspect, and the SLC1A3 inhibitor mentioned earlier also provides an idea to solve this problem