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Reduction in brain lactic acidosis that significantly affects ROS formation is one of the probable mechanisms through which ALC can exert protective effects on brain tissue against oxidative stress damage [20]

While there are many experimental models of permanent drug resistance, there are few that recapitulate the plastic properties of tumor cells that attain resistance and revert after drug discontinuation

1 This medication works to stimulate insulin secretion in a glucose-dependent manner, therefore decreasing the risk of hypoglycemia

10.1186/s12906-016-1111-3

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