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NLC addresses the problems of low solid lipid nanoparticles (SLN) drug load and easy drug leakage while having the slow-release advantage of SLN [51]

[DOI] [PMC free article] [PubMed] [Google Scholar] 170.Pochini L, Scalise M, Galluccio M, Indiveri C

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In addition, comprehensive management of porphyria should also address systemic effects of porphyrin accumulation, such as mitochondrial dysfunction, neurological dysfunction, alterations in glucose, lipid metabolism, insulin resistance, hormonal fluctuations, and proteasomal and autophagic protein aggregation