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By inhibiting cyclooxygenase (COX) enzymes, NSAIDs cause a decrease in the synthesis of prostaglandins that stimulate production of protective mucus and acid-buffering bicarbonate in the digestive tract
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Every subsequent vial (whether you titrate up with us or refill at a maintenance dose) requires us to verify that you are under active medical care for this medication

[DOI] [PubMed] [Google Scholar] Kontogianni MD, Vijayakumar A, Rooney C, Noad RL, Appleton KM, McCarthy D, Donnelly M, Young IS, McKinley MC, McKeown PP, et al