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Solarska K, Lewinska A, Karowicz-Bilinska A, Bartosz G

In cancer cells, mitochondrial function is not entirely impaired, and oxidative phosphorylation and TCA are still functioning [114]

10.1038/5030 Nat

doi:10.1007/s00702-019-02083-z Mansour A, Hariri E, Shelh S, Irani R, Mroueh M

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Beyond skeletal muscle, AICAR-mediated AMPK activation has been implicated in improving insulin sensitivity [152], reducing hepatic lipid accumulation [153], and exerting cytoprotective effects under metabolic stress [154], further underscoring its importance as a molecular probe and potential metabolic modulator