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J Biol Chem 278:24150, PMID: 12414812 Day RM, Suzuki YJ (2006) Cell proliferation, reactive oxygen and cellular glutathione

It is non-transdermal and nothing is absorbed into the skin, it works through the infrared spectrum

GLYT1 receptor is present in the basolateral membrane of enterocytes and its main function is to import glycine into the cells

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Stage III (72-96 hours) = Peak liver toxicity Systemic symptoms reappear (nausea/vomiting, anorexia, malaise)

Therefore, a combination of transcellular and paracellular routes for crossing the nasopharyngeal barrier is also possible if the meningococci crossing via the transcellular route induce a sufficient level of inflammation to alter epithelial permeability, allowing other bacteria to follow the paracellular route