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Description
IGF-1 upregulates PD-L1 via the IGF-1R/AKT/ERK signaling cascade Contrary to its repressive effects on APM genes, IGF-1 significantly induced CD274 (PD-L1) mRNA and surface protein expression in DU145 cells

Maes K, Serre J, Mathyssen C, Janssens W, Gayan-Ramirez G
Often used to help preserve muscle during weight loss or aging

Severe inflammatory ophthalmopathy in a euthyroid patient during nivolumab treatment

Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer

Biomaterials 33, 71267137
