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Systemic oral bioavailability for a 15-amino-acid unprotected peptide is expected to be very low based on general peptide pharmacokinetics

At the end of the day, we will return to Puno, having lived an unforgettable experience in the heart of Lake Titicaca

In this context, expansion of our methodology for peptide designs with further research on ways to improve the incorporation of non-natural amino acids, cyclization and stable peptide bond engineering are crucial

For example, by using changes in body temperature to trigger the release of drugs, personalized disease treatment can be achieved

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Wang AY, Mo X, Chen CS, Yu SM