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Ther Adv Endocrinol Metab 16:20420188251372381 Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS et al (2019) 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

L-carnitine may support fat metabolism, but its effectiveness in burning fat without exercise is limited

Intestinal microorganisms metabolize TML into trimethyl-5-aminovaleric acid (TMAVA), which can competitively inhibit the binding of -BB to BBD, thereby inhibiting carnitine biosynthesis and FAO in the liver, promoting steatosis and aggravating fatty liver [250]
