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Dysregulated TP53 among PTSD patients leads to downregulation of miRNA let-7a and promotes an inflammatory Th17 phenotype

doi: 10.1186/s12937-016-0140-6 128 NiuHLXiaoJY

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Additional funding sources include the Three Lakes Foundation, which is a philanthropic organization with the mission of advancing care for IPF patients by supporting efforts to improve time to diagnosis and accelerate new treatments ( The Pulmonary Fibrosis Foundation is an integral collaborator for this clinical trial as PRECISIONS has the potential to demonstrate the utility of partnering with prospective cohorts to ensure clinical trial enrichment ( In summary, PRECISIONS takes a novel approach to IPF clinical trials by targeting a subgroup of patients with IPF and a specific genotype that may benefit from NAC therapy based on prior pharmaco-genetic studies

Abstract The cohesin complex participates in many structural and functional aspects of genome organization

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