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The Collateral Damage: Allopregnanolone Allopregnanolone (ALLO) is synthesized in the brain from progesterone via a two-step pathway: Progesterone 5-dihydroprogesterone (via 5-alpha reductase) 5-DHP Allopregnanolone (via 3-HSD) Because 5-AR is the rate-limiting step, inhibiting it blocks ALLO productioneven when progesterone levels are adequate

Oral Presentations Oral presentations from the public will begin at approximately 10:15 a.m., 11:50 a.m., 2:15 p.m., and 4:00 p.m

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Role of Vitamin B in Human Health and the Immune System Vitamin B 1 (thiamine) acts as a coenzyme in the pentose phosphate pathway, which is essential for the production of fatty acids, steroids, nucleic acids, and aromatic amino acid precursors, neurotransmitters, and other bioactive compounds that are necessary for brain function [17]