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The interdependence between sleep homeostasis and redox metabolism, in particular, is such that sleep deprivation causes redox metabolic imbalances in the form of over-production of ROS

Possibility of using superoxide dismutase and glutathione peroxidase as endometriosis biomarkers Sophapun Ekarattanawong,1 Chamnan Tanprasertkul,2 Charintip Somprasit,2 Pholasit Chamod,1 Rattana Tiengtip,1 Kornkarn Bhamarapravatana,1 Komsun Suwannarurk2 1Department of Preclinical Science, 2Department of Obstetrics and Gynaecology, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand Objective: To study the possibility of using superoxide dismutase (SOD) and glutathione peroxidase (GPx) as combined preoperative biomarkers for endometriosis

Results To investigate a possible role of the phospholipid hydroperoxidase glutathione peroxidase 4 (GPX4) in protection from oxidative stress, we investigated GPX4 expression in postmortem human brain tissue from individuals with and without Parkinson's disease