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The developmental dependence on iron for reproduction and cellular biochemistry may represent an ancient and conserved liability in late life

Only a few isolated viruses have exhibited resistance to one or two specific NAIs, and these resistant strains have not become dominant in widespread outbreaks

If you must use the degraded solution, assume 25-30% potency loss and adjust expectations accordingly, but understand that results will not be reproducible

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This dynamic underscores the need for monitoring and stress-management strategies during both the early and prolonged phases of KD adherence
