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Moreover, increased expression of TET enzymes, coupled with decreased DNA methyltransferase (DNMT) activity, has been shown to result in the hypomethylation of other immune-related genes such as CTLA-4, further enhancing the suppressive function of Tregs in the tumor microenvironment and promoting tumor progression (Sasidharan Nair et al., 2018

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Yet, it's important to remember that while promising, these benefits are based on available research, and individual outcomes may differ

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