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Side effects are rare

Early on, a dose that's a few days past expiration may retain 95% of its strength

The EM structure of Tirzepatide bound to the complete GIPR and G-proteins (Figure 3, PDB ID 7rbt, Sun et al., 2022) shows some hydrophobic and some specific polar interactions between the peptidic drug and the GIP receptor molecule

Although this amount may seem minor, it must be replenished regularly to prevent deficiencies

The difference between adding 1mL and 2mL of bacteriostatic water does not change the total amount of peptide in the vial, but it dramatically changes how precisely you can measure each dose and how many weeks that vial will last in your refrigerator

a few patients have reported stomach discomfort or loose stools)