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Statements Author contributions VR performed the initial literature search and drafted the original manuscript

Juul-Kristensen, B., Schmedling, K., Rombaut, L., Lund, H

4.4 Immunotherapy for DKD 4.4.1 Cell therapy 4.4.1.1 Treg therapy Tregs play a pivotal role in mitigating immune-mediated renal injury in DKD by suppressing effector T cell activation and restoring immune tolerance
Leroy B, Fournier JL, Ishioka C, Monti P, Inga A, Fronza G, et al

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Such acetylation homeostasis is determined by the interplay between two classes of antagonistic enzymes, histone acetyltransferases (HATs) and histone deacetylases (HDACs), which transfer or remove, respectively, an acetyl moiety of a lysine residue mapping in the N-terminal tail of nucleosomal histones 7
