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Description
Because the final inflated average case-weighted standardized charge per case exceeded the average case-weighted threshold amount, the applicant asserted that REBYOTA TM meets the cost criterion
Chemical shifts were referenced to the residual solvent signal of MeOH- d 3 ( H 3.31/ C 49.0)
R.EichenseherF.TchangV
Similar preclinical studies of mRNA-3705 (for MMA) and mRNA-3210 (for PKU) in mouse models demonstrated strong PK/PD responses, with normalization of respective disease biomarkers and validated allometric models for clinical translation [202]
doi: 10.1016/j.jhep.2022.09.020
doi: 10.1093/beheco/ark016 [DOI] [Google Scholar] 43.McKnight PE, Najab J
