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The European Food Safety Authority (EFSA) has established an acceptable daily intake (ADI) of 3 mg/kg body weight (~210 mg/day for adults) as a conservative threshold (243)

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188 reported that quercetin reduces intracellular ROS production and restores mitochondrial membrane depolarization, thereby alleviating the neurotoxic effects caused by styrene 7,8-oxide

Exome sequencing of an adolescent with neurodegenerative disorder identified a homozygous stop mutation in thioredoxin 2 (Trx2)

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Dilute urine is physiologically appropriate when plasma osmolality is low, prompting suppression of ADH to facilitate free water excretion and prevent hyponatremia