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Even in the unsubstantiated anecdotal reports, any perceived lightening effect is said to fade if the high-dose treatments are discontinued

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Apart from lipid-lowering effects, statins, for example, are able to exert diverse antiinflammatory effects, including inhibition of RhoGTPase that are molecular switches controlling a variety of signal transduction pathways, and, in particular, cholesterol biosynthesis [50], which highlights a close relationship between lipid metabolism and inflammatory processes (Fig

Gusev E, Zhuravleva Y