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In immune cells or stressed tissues, this dysfunction triggers immunometabolic reprogramming

[DOI] [PubMed] [Google Scholar] 26.Hartl D, Starosta V, Maier K, Beck-Speier I, Rebhan C, Becker BF, et al

[DOI] [Google Scholar] Dinges S

Single-target drugs often produce inconsistent results because biological systems are interconnected

Neurospectroscopic alterations have been reported with increase in the Glx/creatine (Cr) ratio accompanied by decrease in myo-inositol (mI)/Cr ratio and total choline (tCho)/Cr ratio in liver disease (30,46,47)

ERS can activate the expression of Ca 2+ release channels on inositol 1,4,5-trisphosphate receptors (IP3R), thereby mediating the release of ER-Ca 2+