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it appears to recapitulate the intracellular signals that exercise generates, including AMPK activation, mitochondrial biogenesis, and GLUT4 upregulation, in tissues that can no longer experience them through movement

group 2: ICA-1s (50 mg/kg)

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The metabolic effects that promote glucose uptake acutely can, with chronic exposure, lead to cells becoming less responsive to insulin's signals

intraperitoneal [111]
