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Description
these complexes primarily include tight junctions (TJs), forming the most apical semi-permeable seal regulating ion and solute passage, adherens junctions (AJs) located subjacent to TJs providing strong mechanical adhesion via cadherin-catenin complexes, and desmosomes acting as anchoring spots providing robust intercellular adhesion along the lateral membranes below AJs.By forming semi-permeable seals within intercellular spaces, TJs selectively permit the paracellular passage of water, ions, and small nutrient molecules while excluding luminal pathogens, toxins, and macromolecular substances from entering underlying tissues

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Komatsu M, Waguri S, Chiba T, et al

H.DvilanskyI.KorenO.ShaharA.GazitR.et al (2023a)

Accordingly, the expression changes of L2HGDH by sg L2HGDH , L2HG treatment, or L2HGDH OPT led to decreased or increased DNA hydroxymethylation in the CBS promoter CpG island (Fig

Panka DJ, Wang W, Atkins MB, Mier JW
