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In the mitochondria, a measurable steady-state efflux of H 2 O 2 occurs even under resting conditions, which is derived from O 2 dismutation by SOD2 and intercompartmental exchange (Fig
Deng, & C
Apart from this, melatonin affects Nrf2 via the inhibition of degradation and the promotion of its nuclear translocation [29,31,34]
10.1038/s41586-018-0620-2 152 VatanenT.De BeaufortC.MarcovecchioM
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